Endocrine Abstracts

A 27 years old primigravida, with no significant past medical history, was referred to Endocrine clinic at 37 weeks gestation with hirsutism. She developed hirsute features during pregnancy and symptoms progressed with advancing gestation. Her physical examination revealed thick coarse dark hair growth in the midline of lower abdomen, between the breasts and forearms. She noted deepening of her voice but denied headaches, visual disturbance or clitromegaly.<...

A 27 years old primigravida, with no significant past medical history, was referred to Endocrine clinic at 37 weeks gestation with hirsutism. She developed hirsute features during pregnancy and symptoms progressed with advancing gestation. Her physical examination revealed thick coarse dark hair growth in the midline of lower abdomen, between the breasts and forearms. She noted deepening of her voice but denied headaches, visual disturbance or clitromegaly.<...

According to the seventh edition of diabetes atlas, 415 million persons all over the world are diabetics requiring more than 680 billion US $ annually for their management. Diabetes affects middle and low socio economic countries than developed countries. The ADA/EASD guidelines included drug price as one of the criteria to choose from different classes. Incretin based therapy are new classes for treatment of T2 DM with low incidence of hypoglycemia and modest weight loss, but...

Case History: 37 years old female, presented to Emergency department with worsening SOB over last 24 hours. On systemic enquiry, patient complained of epigastric pain after eating and admitted to un-intentional 22 Kg weight loss in last four months. She clinically appeared dehydrated, with mild epigastric tenderness and no other abnormal signs. She denied any alcohol ingestion or illicit drug use. She had treated Vitamin B12 deficiency and idi...

We present a challenging case of a 51 years old men, diagnosed with diabetes as he presented to emergency department with osmotic symptoms and hyperglycaemia. He was started on insulin and referred to diabetes clinic.On review, glycaemic control was sub-optimal (HbA1c 94 mmol/mol) and his insulin was changed from biphasic to basal-bolus regimen. His BMI was 21 kg/m2 and no family history of diabetes was report...

Case History: 37 years old female, presented to Emergency department with worsening SOB over last 24 hours. On systemic enquiry, patient complained of epigastric pain after eating and admitted to un-intentional 22 Kg weight loss in last four months. She clinically appeared dehydrated, with mild epigastric tenderness and no other abnormal signs. She denied any alcohol ingestion or illicit drug use. She had treated Vitamin B12 deficiency and idi...

We present a challenging case of a 51 years old men, diagnosed with diabetes as he presented to emergency department with osmotic symptoms and hyperglycaemia. He was started on insulin and referred to diabetes clinic.On review, glycaemic control was sub-optimal (HbA1c 94 mmol/mol) and his insulin was changed from biphasic to basal-bolus regimen. His BMI was 21 kg/m2 and no family history of diabetes was report...

Introduction: The mutation at m. 3243 adenine to guanine (A>G) in mitochondrial encoded transfer-RNA Leucine 1 (MTTL1) gene is the single most prevalent disease-causing mitochondrial DNA (MtDNA) mutation, with carrier status of 1:400 in our general population. The distinct disease phenotype is dependent on the level of heteroplasmy of wild-type vs mutation-type mtDNA in the specific target tissues, ranging from Maternally inherited diabetes and Deafness (MIDD) to mitochond...

Background: Insulinoma in a pre existing patient of type diabetes is extremely rare presentation.Methods: We are presenting a a rare case of insulinoma in a pre existing case of type 2 diabetes. A 73 years old patient with type 2 diabetes for 35 years presented to endocrine clinic with hypoglycaemic symptoms ultimatley diagnosed with insulinoma and patient developed renal failure with diazoxide treatment.Result: A 73 years old chin...

Aims: To evaluate the prevalence of depression and anxiety in adult outpatients with diabetes and identify the correlation with diabetes management behaviours and clinical outcomes.Methods: Cross-sectional analyses were performed on 142 diabetic patients (type 1 diabetes n=67, type 2 diabetes n=60) attending outpatient clinic. Depression and anxiety were evaluated using the Patient Health Questionnaire (PHQ-2) and the General Anxiety Di...